Resources

Links:

Addgene: The nonprofit plasmid depository

Biomedical Sciences Ph.D. Program  at FSU College of Medicine

FSU College of Medicine

FSU Translational Science Laboratory

Single-cell RNA-seq of the human pancreas:

1. GSE73727: Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types. 

2. GSE81076: De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data. 

3. GSE81547 : Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns.

4. GSE81608: RNA Sequencing of Single Human Islet Cells Reveals Type 2 Diabetes Genes.

5. GSE83139: Single-Cell Transcriptomics of the Human Endocrine Pancreas.

6. GSE84133: A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure.

7. GSE85241: A Single-Cell Transcriptome Atlas of the Human Pancreas. 

8. GSE86473: Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.

9. GSE97655: Single-cell transcriptomics of East-Asian pancreatic islets cells.

10. GSE101207: Single-Cell Heterogeneity Analysis and CRISPR Screen Identify Key β-Cell-Specific Disease Genes.

11. GSE114297: Pseudotime Ordering of Single Human β-Cells Reveals States of Insulin Production and Unfolded Protein Response.

12. E-MTAB-5061 : Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes

13. GSE124742: Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes.

14. GSE131886: Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche.

15. GSE134355: Construction of a human cell landscape at single-cell level.

16. GSE147203: Single-cell RNA-seq with spike-in cells enables accurate quantification of cell-specific drug effects in pancreatic islets. 

17. GSE147349: single-cell mRNA sequencing of human embryonic pancreas

18. EGAD00001006396 (Link for Seurat object): Single nucleus and in situ RNA sequencing reveals cell topographies in the human pancreas

19. GSE154126: Single cell transcriptomics of human islet ontogeny defines the molecular basis of beta cell dedifferentiation in T2D

20. HPAP portal

21. CellxGene: A transcriptional cross species map of pancreatic islet cells

22. GSE156793: A human cell atlas of fetal gene expression

Bulk RNA-seq of the human pancreas:

1. GSE76268: Integration of ATAC-seq and RNA-seq identifies human alpha cell and beta cell signature genes.

2. GSE121863: HLA Class II analysis of human pancreatic beta cells

3. GSE159984: Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes.

4. TIGER Data Portal

Protocols: